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Nucleophilicity of Glutathione: A Link to Michael Acceptor Reactivities

Deprotonated glutathione is among the most potent biological nucleophiles and plays an important physiological role in cellular detoxification by forming covalent conjugates with Michael acceptors. The electrophilicity E of various Michael acceptors was characterized recently according to the Patz–M...

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Detalles Bibliográficos
Autores principales:	Mayer, Robert J., Ofial, Armin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899611/ https://www.ncbi.nlm.nih.gov/pubmed/31560405 http://dx.doi.org/10.1002/anie.201909803

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