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Synthesis of Gb(3) Glycosphingolipids with Labeled Head Groups: Distribution in Phase‐Separated Giant Unilamellar Vesicles

The receptor lipid Gb(3) is responsible for the specific internalization of Shiga toxin (STx) into cells. The head group of Gb(3) defines the specificity of STx binding, and the backbone with different fatty acids is expected to influence its localization within membranes impacting membrane organiza...

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Detalles Bibliográficos
Autores principales: Sibold, Jeremias, Kettelhoit, Katharina, Vuong, Loan, Liu, Fangyuan, Werz, Daniel B., Steinem, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899692/
https://www.ncbi.nlm.nih.gov/pubmed/31529754
http://dx.doi.org/10.1002/anie.201910148