Exosomal Transport of Hepatocyte‐Derived Drug‐Modified Proteins to the Immune System

Idiosyncratic drug‐induced liver injury (DILI) is a rare, often difficult‐to‐predict adverse reaction with complex pathomechanisms. However, it is now evident that certain forms of DILI are immune‐mediated and may involve the activation of drug‐specific T cells. Exosomes are cell‐derived vesicles th...

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Detalles Bibliográficos
Autores principales: Ogese, Monday O., Jenkins, Rosalind E., Adair, Kareena, Tailor, Arun, Meng, Xiaoli, Faulkner, Lee, Enyindah, Bright O., Schofield, Amy, Diaz‐Nieto, Rafael, Ressel, Lorenzo, Eagle, Gina L., Kitteringham, Neil R., Goldring, Chris E., Park, B. Kevin, Naisbitt, Dean J., Betts, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899733/
https://www.ncbi.nlm.nih.gov/pubmed/31070244
http://dx.doi.org/10.1002/hep.30701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899733/
https://www.ncbi.nlm.nih.gov/pubmed/31070244
http://dx.doi.org/10.1002/hep.30701

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