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The differential distributions of ASPM isoforms and their roles in Wnt signaling, cell cycle progression, and pancreatic cancer prognosis

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and treatment‐resistant malignancy. The lack of pathway‐informed biomarkers hampers the development of rational diagnostics or therapies. Recently, the protein abnormal spindle‐like microcephaly‐associated (ASPM) was identified as a nove...

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Detalles Bibliográficos
Autores principales: Hsu, Chung‐Chi, Liao, Wen‐Ying, Chan, Tze‐Sian, Chen, Wei‐Yu, Lee, Chung‐Ta, Shan, Yan‐Shen, Huang, Po‐Jui, Hou, Ya‐Chin, Li, Chi‐Rong, Tsai, Kelvin K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899738/
https://www.ncbi.nlm.nih.gov/pubmed/31465125
http://dx.doi.org/10.1002/path.5341