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Rapamycin attenuates the paraquat‐induced pulmonary fibrosis through activating Nrf2 pathway

Oxidative stress is a key regulator of idiopathic pulmonary fibrosis. Paraquat (PQ)‐induced pulmonary fibrosis seriously endangers people's health. Rapamycin has been reported to alleviate PQ‐induced pulmonary fibrosis, but its underlying mechanism is unclear. The nuclear factor E2‐related fact...

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Detalles Bibliográficos
Autores principales: Tai, Wenlin, Deng, Shuhao, Wu, Wenjuan, Li, ZhenKun, Lei, Wen, Wang, Yin, Vongphouttha, Chanthasone, Zhang, Tao, Dong, Zhaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899830/
https://www.ncbi.nlm.nih.gov/pubmed/31301076
http://dx.doi.org/10.1002/jcp.29094