Cargando…

Age‐ and disease‐specific changes of the kynurenine pathway in Parkinson’s and Alzheimer’s disease

The kynurenine (Kyn) pathway, which regulates neuroinflammation and N‐methyl‐d‐aspartate receptor activation, is implicated in Parkinson’s disease (PD) and Alzheimer’s disease (AD). Age‐related changes in Kyn metabolism and altered cerebral Kyn uptake along large neutral amino acid transporters, cou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sorgdrager, Freek J. H., Vermeiren, Yannick, Van Faassen, Martijn, van der Ley, Claude, Nollen, Ellen A. A., Kema, Ido P., De Deyn, Peter P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899862/ https://www.ncbi.nlm.nih.gov/pubmed/31376341 http://dx.doi.org/10.1111/jnc.14843

Ejemplares similares

The Effect of Tryptophan 2,3-Dioxygenase Inhibition on Kynurenine Metabolism and Cognitive Function in the APP23 Mouse Model of Alzheimer’s Disease
por: Sorgdrager, FJH, et al.
Publicado: (2020)

Brain Kynurenine Pathway Metabolite Levels May Reflect Extent of Neuroinflammation in ALS, FTD and Early Onset AD
por: Heylen, Annelies, et al.
Publicado: (2023)

Monoaminergic and Kynurenergic Characterization of Frontotemporal Dementia and Amyotrophic Lateral Sclerosis in Cerebrospinal Fluid and Serum
por: Janssens, Jana, et al.
Publicado: (2020)

Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target
por: Sorgdrager, Freek J. H., et al.
Publicado: (2019)

In Matrix Derivatization Combined with LC-MS/MS Results in Ultrasensitive Quantification of Plasma Free Metanephrines and Catecholamines
por: van Faassen, Martijn, et al.
Publicado: (2020)

Serotonergic Dysfunction in Amyotrophic Lateral Sclerosis and Parkinson's Disease: Similar Mechanisms, Dissimilar Outcomes
por: Vermeiren, Yannick, et al.
Publicado: (2018)

Biofluid Markers for Prodromal Parkinson's Disease: Evidence From a Catecholaminergic Perspective
por: Vermeiren, Yannick, et al.
Publicado: (2020)

Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα
por: Cai, Zongye, et al.
Publicado: (2022)

Identification of an evolutionary conserved structural loop that is required for the enzymatic and biological function of tryptophan 2,3-dioxygenase
por: Michels, Helen, et al.
Publicado: (2016)

The monoaminergic footprint of depression and psychosis in dementia with Lewy bodies compared to Alzheimer’s disease
por: Vermeiren, Yannick, et al.
Publicado: (2015)

Neuropsychiatric Disturbances in Alzheimer’s Disease: What Have We Learned from Neuropathological Studies?
por: Van Dam, Debby, et al.
Publicado: (2016)

An antibody-free LC-MS/MS method for the quantification of intact insulin-like growth factors 1 and 2 in human plasma
por: Pratt, Mark S., et al.
Publicado: (2021)

The Anaesthetic Biobank of Cerebrospinal fluid: a unique repository for neuroscientific biomarker research
por: Tigchelaar, Celien, et al.
Publicado: (2021)

Cerebrospinal fluid and serum MHPG improve Alzheimer's disease versus dementia with Lewy bodies differential diagnosis
por: Janssens, Jana, et al.
Publicado: (2018)

Kynurenines, neurodegeneration and Alzheimer’s disease
por: Kincses, Zsigmond Tamas, et al.
Publicado: (2010)

Kynurenine pathway in Parkinson's disease—An update
por: Venkatesan, Dhivya, et al.
Publicado: (2020)

Residual endogenous corticosteroid production in patients with adrenal insufficiency
por: Vulto, Annet, et al.
Publicado: (2019)

Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease
por: Dekker, Alain D., et al.
Publicado: (2017)

The Involvement of Neuroinflammation and Kynurenine Pathway in Parkinson's Disease
por: Zinger, Anna, et al.
Publicado: (2011)

Kynurenine Pathway Metabolites as Biomarkers in Alzheimer's Disease
por: Liang, Yuqing, et al.
Publicado: (2022)

Selective quantification of the 22-kDa isoform of human growth hormone 1 in serum and plasma by immunocapture and LC–MS/MS
por: Sleumer, Bas, et al.
Publicado: (2022)

Serum Daytime Melatonin Levels Reflect Cerebrospinal Fluid Melatonin Levels in Alzheimer’s Disease but Are Not Correlated with Cognitive Decline
por: Nous, Amber, et al.
Publicado: (2021)

Gonadal steroid levels in rock pigeon eggs do not represent adequately maternal allocation
por: Kumar, Neeraj, et al.
Publicado: (2018)

Plasticity in metabolism of maternal androgens in avian embryos
por: Wang, Yuqi, et al.
Publicado: (2023)

Development and Interlaboratory Validation of Two Fast UPLC–MS-MS Methods Determining Urinary Bisphenols, Parabens and Phthalates
por: van der Meer, Thomas P, et al.
Publicado: (2019)

Exposure to Endocrine Disrupting Chemicals in the Dutch general population is associated with adiposity-related traits
por: van der Meer, Thomas P., et al.
Publicado: (2020)

The Impact of Goal Disturbance after Cancer on Cortisol Levels over Time and the Moderating Role of COMT
por: Janse, Moniek, et al.
Publicado: (2015)

Dynamic changes in metabolites of the kynurenine pathway in Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease: A systematic Review and meta-analysis
por: Fathi, Mobina, et al.
Publicado: (2022)

Neutrophil Gelatinase-Associated Lipocalin and its Receptors in Alzheimer’s Disease (AD) Brain Regions: Differential Findings in AD with and without Depression
por: Dekens, Doortje W., et al.
Publicado: (2016)

Hypoxia and the Kynurenine Pathway: Implications and Therapeutic Prospects in Alzheimer's Disease
por: Adeyemi, Oluyomi Stephen, et al.
Publicado: (2021)

Urinary Excretion of 6-Sulfatoxymelatonin, the Main Metabolite of Melatonin, and Mortality in Stable Outpatient Renal Transplant Recipients
por: van der Veen, Anna, et al.
Publicado: (2020)

Research progress on the kynurenine pathway in the prevention and treatment of Parkinson’s disease
por: Chen, Ping, et al.
Publicado: (2023)

Concentration gradients of monoamines, their precursors and metabolites in serial lumbar cerebrospinal fluid of neurologically healthy patients determined with a novel LC–MS/MS technique
por: Tigchelaar, Celien, et al.
Publicado: (2023)

Reference intervals for plasma, urinary, and salivary concentrations of free metanephrines in dogs: Relevance to the diagnosis of pheochromocytoma
por: van den Berg, Marit F., et al.
Publicado: (2023)

The Genetic Link between Parkinson's Disease and the Kynurenine Pathway Is Still Missing
por: Török, Nóra, et al.
Publicado: (2015)

Cortisol and α-Amylase Secretion Patterns between and within Depressed and Non-Depressed Individuals
por: Booij, Sanne H., et al.
Publicado: (2015)

Withdrawn: The novel TRPA1 antagonist BI01305834 inhibits ovalbumin‐induced bronchoconstriction in guinea pigs
por: van den Berg, Mariska, et al.
Publicado: (2020)

Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease
por: Gerrits, Emma, et al.
Publicado: (2021)

The kynurenine pathway in Alzheimer’s disease: a meta-analysis of central and peripheral levels
por: Fernandes, Brisa S., et al.
Publicado: (2023)

Kynurenine pathway in kidney diseases
por: Zakrocka, Izabela, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jbj47q45f95p1cvgcdkgqckjae