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Interleukin‐2 induces extracellular matrix synthesis and TGF‐β2 expression in retinal pigment epithelial cells

Macular fibrosis is a vital obstacle of vision acuity improvement of age‐related macular degeneration patients. This study was to investigate the effects of interleukin 2 (IL‐2) on epithelial‐mesenchymal transition (EMT), extracellular matrix (ECM) synthesis and transforming growth factor β2 (TGF‐β2...

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Detalles Bibliográficos
Autores principales: Jing, Ruihua, Qi, Tiantian, Wen, Chan, Yue, Jiaqi, Wang, Guangyan, Pei, Cheng, Ma, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899885/
https://www.ncbi.nlm.nih.gov/pubmed/31608440
http://dx.doi.org/10.1111/dgd.12630