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Defective fibrin deposition and thrombus stability in Bambi (−/−) mice are mediated by elevated anticoagulant function

BACKGROUND: Bone morphogenetic and activin membrane‐bound inhibitor (BAMBI) is a transmembrane protein related to the type I transforming growth factor‐ β (TGF‐β) receptor family that is present on both platelets and endothelial cells (ECs). Bambi‐deficient mice exhibit reduced hemostatic function a...

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Detalles Bibliográficos
Autores principales: Crawley, James T. B., Zalli, Argita, Monkman, James H., Petri, Anastasis, Lane, David A., Ahnstrӧm, Josefin, Salles‐Crawley, Isabelle I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899896/
https://www.ncbi.nlm.nih.gov/pubmed/31351019
http://dx.doi.org/10.1111/jth.14593