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Application of affinity capillary electrophoresis for charge heterogeneity profiling of biopharmaceuticals

Charge heterogeneity profiling is important for the quality control (QC) of biopharmaceuticals. Because of the increasing complexity of these therapeutic entities [1], the development of alternative analytical techniques is needed. In this work, flow‐through partial‐filling affinity capillary electr...

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Detalles Bibliográficos
Autores principales: Hutanu, Andrei, Kiessig, Steffen, Bathke, Andrea, Ketterer, Rolf, Riner, Sonja, Olaf Stracke, Jan, Wild, Markus, Moritz, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900010/
https://www.ncbi.nlm.nih.gov/pubmed/31560789
http://dx.doi.org/10.1002/elps.201900233