Effects of ibrutinib on proliferation and histamine release in canine neoplastic mast cells

The Bruton's tyrosine kinase (BTK) inhibitor ibrutinib is effective in the treatment of human chronic lymphocytic leukaemia and mantle cell lymphoma. Recent data have shown that ibrutinib also blocks IgE‐dependent activation and histamine release in human basophils (BAs) and mast cells (MCs). T...

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Detalles Bibliográficos
Autores principales: Gamperl, Susanne, Stefanzl, Gabriele, Peter, Barbara, Smiljkovic, Dubravka, Bauer, Karin, Willmann, Michael, Valent, Peter, Hadzijusufovic, Emir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900099/
https://www.ncbi.nlm.nih.gov/pubmed/31286638
http://dx.doi.org/10.1111/vco.12520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900099/
https://www.ncbi.nlm.nih.gov/pubmed/31286638
http://dx.doi.org/10.1111/vco.12520

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