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Impacts of intentional mycoplasma contamination on CHO cell bioreactor cultures

Mycoplasma contamination events in biomanufacturing facilities can result in loss of production and costly cleanups. Mycoplasma may survive in mammalian cell cultures with only subtle changes to the culture and may penetrate the 0.2 µm filters often used in the primary clarification of harvested cel...

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Detalles Bibliográficos
Autores principales: Fratz‐Berilla, Erica J., Faison, Talia, Kohnhorst, Casey L., Velugula‐Yellela, Sai Rashmika, Powers, David N., Brorson, Kurt, Agarabi, Cyrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900124/
https://www.ncbi.nlm.nih.gov/pubmed/31478189
http://dx.doi.org/10.1002/bit.27161