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Overactivity or blockade of transforming growth factor‐β each generate a specific ureter malformation

Transforming growth factor‐β (TGFβ) has been reported to be dysregulated in malformed ureters. There exists, however, little information on whether altered TGFβ levels actually perturb ureter development. We therefore hypothesised that TGFβ has functional effects on ureter morphogenesis. Tgfb1, Tgfb...

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Detalles Bibliográficos
Autores principales: Lopes, Filipa M, Roberts, Neil A, Zeef, Leo AH, Gardiner, Natalie J, Woolf, Adrian S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900140/
https://www.ncbi.nlm.nih.gov/pubmed/31400222
http://dx.doi.org/10.1002/path.5335