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Mode‐of‐action analysis of the effects induced by nicotine in the in vitro micronucleus assay

Nicotine's genotoxic potential has been extensively studied in vitro. While the results of mammalian cell‐based studies have inferred that it can potentially damage chromosomes, in general and with few exceptions, adverse DNA effects have been observed primarily at supraphysiological concentrat...

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Detalles Bibliográficos
Autores principales: Smart, Daniel J., Helbling, Fabian R., Verardo, Maëlle, McHugh, Damian, Vanscheeuwijck, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900147/
https://www.ncbi.nlm.nih.gov/pubmed/31294873
http://dx.doi.org/10.1002/em.22314