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Mode‐of‐action analysis of the effects induced by nicotine in the in vitro micronucleus assay
Nicotine's genotoxic potential has been extensively studied in vitro. While the results of mammalian cell‐based studies have inferred that it can potentially damage chromosomes, in general and with few exceptions, adverse DNA effects have been observed primarily at supraphysiological concentrat...
Autores principales: | Smart, Daniel J., Helbling, Fabian R., Verardo, Maëlle, McHugh, Damian, Vanscheeuwijck, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900147/ https://www.ncbi.nlm.nih.gov/pubmed/31294873 http://dx.doi.org/10.1002/em.22314 |
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