A Fluorescent Activatable AND‐Gate Chemokine CCL2 Enables In Vivo Detection of Metastasis‐Associated Macrophages

We report the novel chemical design of fluorescent activatable chemokines as highly specific functional probes for imaging subpopulations of immune cells in live tumours. Activatable chemokines behave as AND‐gates since they emit only after receptor binding and intracellular activation, showing enha...

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Detalles Bibliográficos
Autores principales: Fernandez, Antonio, Thompson, Emily J., Pollard, Jeffrey W., Kitamura, Takanori, Vendrell, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900180/
https://www.ncbi.nlm.nih.gov/pubmed/31535788
http://dx.doi.org/10.1002/anie.201910955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900180/
https://www.ncbi.nlm.nih.gov/pubmed/31535788
http://dx.doi.org/10.1002/anie.201910955

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