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A WHO Reference Reagent for lupus (anti-dsDNA) antibodies: international collaborative study to evaluate a candidate preparation

INTRODUCTION: Antibodies against double-stranded DNA (anti-dsDNA) are a specific biomarker for systemic lupus erythematosus (SLE). The first WHO International Standard (IS) for anti-dsDNA (established in 1985), which was used to assign units to diagnostic tests, was exhausted over a decade ago. METH...

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Detalles Bibliográficos
Autores principales: Fox, Bernard J, Hockley, Jason, Rigsby, Peter, Dolman, Carl, Meroni, Pier Luigi, Rönnelid, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900249/
https://www.ncbi.nlm.nih.gov/pubmed/31488407
http://dx.doi.org/10.1136/annrheumdis-2019-215845