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Immunome perturbation is present in patients with juvenile idiopathic arthritis who are in remission and will relapse upon anti-TNFα withdrawal

OBJECTIVES: Biologics treatment with antitumour necrosis factor alpha (TNFα) is efficacious in patients with juvenile idiopathic arthritis (JIA). Despite displaying clinical inactivity during treatment, many patients will flare on cessation of therapy. The inability to definitively discriminate pati...

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Detalles Bibliográficos
Autores principales: Leong, Jing Yao, Chen, Phyllis, Yeo, Joo Guan, Ally, Fauziah, Chua, Camillus, Nur Hazirah, Sharifah, Poh, Su Li, Pan, Lu, Lai, Liyun, Lee, Elene Seck Choon, Bathi, Loshinidevi D/O Thana, Arkachaisri, Thaschawee, Lovell, Daniel, Albani, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900250/
https://www.ncbi.nlm.nih.gov/pubmed/31540934
http://dx.doi.org/10.1136/annrheumdis-2019-216059