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Machine learning predicts putative hematopoietic stem cells within large single-cell transcriptomics data sets

Hematopoietic stem cells (HSCs) are an essential source and reservoir for normal hematopoiesis, and their function is compromised in many blood disorders. HSC research has benefitted from the recent development of single-cell molecular profiling technologies, where single-cell RNA sequencing (scRNA-...

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Detalles Bibliográficos
Autores principales: Hamey, Fiona K., Göttgens, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900257/
https://www.ncbi.nlm.nih.gov/pubmed/31513832
http://dx.doi.org/10.1016/j.exphem.2019.08.009