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From EST to structure models for functional inference of APP, BACE1, PSEN1, PSEN2 genes

Successive oxidative stress and biochemical changes results in neuronal death and neuritic plaques growth in Alzheimer's disease (AD). Therefore, it is interest to analyze amyloid-βeta precursor protein (APP), beta-secretase 1 (BACE1), presenilin (PSEN1 and PSEN2) genes from brain tissues to ga...

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Detalles Bibliográficos
Autores principales: Aathi, Muthusankar, Piramanayagam, Shanmughavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900319/
https://www.ncbi.nlm.nih.gov/pubmed/31831959
http://dx.doi.org/10.6026/97320630015760