Gain of function in somatic TP53 mutations is associated with immune‐rich breast tumors and changes in tumor‐associated macrophages

BACKGROUND: Somatic mutations in TP53 are present in 20%–30% of all breast tumors. While there are numerous population‐based analyses of TP53, yet none have examined the relationship between somatic mutations in TP53 and tumor invasive immune cells. METHODS: Clinical and genetic data from 601 women...

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Detalles Bibliográficos
Autores principales: Behring, Michael, Vazquez, Ana I., Cui, Xiangqin, Irvin, Marguerite R., Ojesina, Akinyemi I., Agarwal, Sumit, Manne, Upender, Shrestha, Sadeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900370/
https://www.ncbi.nlm.nih.gov/pubmed/31637877
http://dx.doi.org/10.1002/mgg3.1001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900370/
https://www.ncbi.nlm.nih.gov/pubmed/31637877
http://dx.doi.org/10.1002/mgg3.1001

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