NEDD4 Negatively Regulates GITR via Ubiquitination in Immune Microenvironment of Melanoma

INTRODUCTION: Melanoma is a common skin cancer that is usually associated with poor clinical outcomes. Recently, the immune checkpoint GITR has been identified as a promising target for immunotherapy of melanoma. In this study, we aimed to investigate the post-translational regulation mechanism of G...

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Detalles Bibliográficos
Autores principales: Guo, Yu, Yang, Lichang, Lei, Shaorong, Tan, Wuyuan, Long, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900405/
https://www.ncbi.nlm.nih.gov/pubmed/31824170
http://dx.doi.org/10.2147/OTT.S212317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900405/
https://www.ncbi.nlm.nih.gov/pubmed/31824170
http://dx.doi.org/10.2147/OTT.S212317

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