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Toxic Effects of Methotrexate on Rat Kidney Recovered by Crocin as a Consequence of Antioxidant Activity and Lipid Peroxidation Prevention

BACKGROUND: The application of MTX as a chemotherapy agent and immune system suppressant has various side effects. Crocin, a xanthine derivative plant, has many therapeutic benefits. This study was planned to assess the effect of crocin on renal toxicity of MTX in a rat model. METHODS: Forty eight r...

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Detalles Bibliográficos
Autores principales: Jalili, Cyrus, Ghanbari, Ali, Roshankhah, Shiva, Salahshoor, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900476/
https://www.ncbi.nlm.nih.gov/pubmed/31454862
http://dx.doi.org/10.29252/ibj.24.1.39