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Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and responses to hypoxia

Secreted exosomal microRNAs (miRNAs) mediate interorgan/tissue communications by modulating target gene expression, thereby regulating developmental and physiological functions. However, the source, route, and function in target cells have not been formally established for specific miRNAs. Here, we...

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Detalles Bibliográficos
Autores principales: Tsai, Yi-Wei, Sung, Hsin-Ho, Li, Jian-Chiuan, Yeh, Chun-Yen, Chen, Pei-Yi, Cheng, Ying-Ju, Chen, Chun-Hong, Tsai, Yu-Chen, Chien, Cheng-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900535/
https://www.ncbi.nlm.nih.gov/pubmed/31666321
http://dx.doi.org/10.1073/pnas.1902537116