Mechanistic insights into mRNA 3′-end processing

The polyadenosine (poly(A)) tail found on the 3′-end of almost all eukaryotic mRNAs is important for mRNA stability and regulation of translation. mRNA 3′-end processing occurs co-transcriptionally and involves more than 20 proteins to specifically recognize the polyadenylation site, cleave the pre-...

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Detalles Bibliográficos
Autores principales: Kumar, Ananthanarayanan, Clerici, Marcello, Muckenfuss, Lena M, Passmore, Lori A, Jinek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900580/
https://www.ncbi.nlm.nih.gov/pubmed/31499460
http://dx.doi.org/10.1016/j.sbi.2019.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900580/
https://www.ncbi.nlm.nih.gov/pubmed/31499460
http://dx.doi.org/10.1016/j.sbi.2019.08.001

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