Cargando…
Mechanistic insights into mRNA 3′-end processing
The polyadenosine (poly(A)) tail found on the 3′-end of almost all eukaryotic mRNAs is important for mRNA stability and regulation of translation. mRNA 3′-end processing occurs co-transcriptionally and involves more than 20 proteins to specifically recognize the polyadenylation site, cleave the pre-...
Autores principales: | Kumar, Ananthanarayanan, Clerici, Marcello, Muckenfuss, Lena M, Passmore, Lori A, Jinek, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900580/ https://www.ncbi.nlm.nih.gov/pubmed/31499460 http://dx.doi.org/10.1016/j.sbi.2019.08.001 |
Ejemplares similares
-
Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3′ end biogenesis
por: Muckenfuss, Lena Maria, et al.
Publicado: (2022) -
Dynamics in Fip1 regulate eukaryotic mRNA 3′ end processing
por: Kumar, Ananthanarayanan, et al.
Publicado: (2021) -
Architecture of eukaryotic mRNA 3′-end processing machinery
por: Casañal, Ana, et al.
Publicado: (2017) -
3′-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression
por: Boreikaitė, Vytautė, et al.
Publicado: (2023) -
RBBP6 activates the pre-mRNA 3′ end processing machinery in humans
por: Boreikaite, Vytaute, et al.
Publicado: (2022)