Statistical Methods for Adjusting Estimates of Treatment Effectiveness for Patient Nonadherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Systematic Review of Methodological Papers

Introduction. Medication nonadherence can have a significant negative impact on treatment effectiveness. Standard intention-to-treat analyses conducted alongside clinical trials do not make adjustments for nonadherence. Several methods have been developed that attempt to estimate what treatment effe...

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Detalles Bibliográficos
Autores principales: Alshreef, Abualbishr, Latimer, Nicholas, Tappenden, Paul, Wong, Ruth, Hughes, Dyfrig, Fotheringham, James, Dixon, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900590/
https://www.ncbi.nlm.nih.gov/pubmed/31646932
http://dx.doi.org/10.1177/0272989X19881654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900590/
https://www.ncbi.nlm.nih.gov/pubmed/31646932
http://dx.doi.org/10.1177/0272989X19881654

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