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Human neutrophils depend on extrinsic factors produced by monocytes for their survival response to TLR4 stimulation

LPS delays neutrophil apoptosis by a process generally assumed to involve cell-intrinsic TLR4 signaling. However, neutrophil survival responses to LPS have been reported to be monocyte-dependent, which would indicate more complexity than is currently appreciated. We compared the survival responses o...

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Detalles Bibliográficos
Autores principales: SenGupta, Shuvasree, Rane, Madhavi J, Uriarte, Silvia M, Woolley, Cassandra, Mitchell, Thomas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900669/
https://www.ncbi.nlm.nih.gov/pubmed/31480890
http://dx.doi.org/10.1177/1753425919871994