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Choline Attenuates Cardiac Fibrosis by Inhibiting p38MAPK Signaling Possibly by Acting on M(3) Muscarinic Acetylcholine Receptor

Choline has been reported to produce a variety of cellular functions including cardioprotection via activating M(3) muscarinic acetylcholine receptor (M(3)R) under various insults. However, whether choline offers similar beneficial effects via the same mechanism in cardiac fibrosis remained unexplor...

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Detalles Bibliográficos
Autores principales: Zhao, Lihui, Chen, Tingting, Hang, Pengzhou, Li, Wen, Guo, Jing, Pan, Yang, Du, Jingjing, Zheng, Yuyang, Du, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900736/
https://www.ncbi.nlm.nih.gov/pubmed/31849653
http://dx.doi.org/10.3389/fphar.2019.01386