Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria

Oligoribonucleases are conserved enzymes that degrade short RNA molecules of up to 5 nt in length and are assumed to constitute the final stage of RNA turnover. Here we demonstrate that REXO2 is a specialized dinucleotide-degrading enzyme that shows no preference between RNA and DNA dinucleotide sub...

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Detalles Bibliográficos
Autores principales: Nicholls, Thomas J., Spåhr, Henrik, Jiang, Shan, Siira, Stefan J., Koolmeister, Camilla, Sharma, Sushma, Kauppila, Johanna H.K., Jiang, Min, Kaever, Volkhard, Rackham, Oliver, Chabes, Andrei, Falkenberg, Maria, Filipovska, Aleksandra, Larsson, Nils-Göran, Gustafsson, Claes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900737/
https://www.ncbi.nlm.nih.gov/pubmed/31588022
http://dx.doi.org/10.1016/j.molcel.2019.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900737/
https://www.ncbi.nlm.nih.gov/pubmed/31588022
http://dx.doi.org/10.1016/j.molcel.2019.09.010

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