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Effects of N-acetylcysteine on amphetamine-induced sensitization in mice

OBJECTIVE: N-acetylcysteine (NAC) is beneficial in psychiatric conditions, including schizophrenia. Patients with schizophrenia exhibit mesolimbic dopamine hyperfunction consequent to an endogenous sensitization process. This sensitization can be modeled in rodents by repeated exposure to psychostim...

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Detalles Bibliográficos
Autores principales: Herrmann, Ana P., Andrejew, Roberta, Benvenutti, Radharani, Gama, Clarissa S., Elisabetsky, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Psiquiatria 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900759/
https://www.ncbi.nlm.nih.gov/pubmed/29236922
http://dx.doi.org/10.1590/1516-4446-2017-2337