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Molecular networks of FOXP family: dual biologic functions, interplay with other molecules and clinical implications in cancer progression

Though Forkhead box P (FOXP) transcription factors comprising of FOXP1, FOXP2, FOXP3 and FOXP4 are involved in the embryonic development, immune disorders and cancer progression, the underlying function of FOXP3 targeting CD4 + CD25+ regulatory T (Treg) cells and the dual roles of FOXP proteins as a...

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Detalles Bibliográficos
Autores principales: Kim, Ju-Ha, Hwang, Jisung, Jung, Ji Hoon, Lee, Hyo-Jung, Lee, Dae Young, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900861/
https://www.ncbi.nlm.nih.gov/pubmed/31815635
http://dx.doi.org/10.1186/s12943-019-1110-3