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An analysis of mutational signatures of synonymous mutations across 15 cancer types

BACKGROUND: Synonymous mutations have been identified to play important roles in cancer development, although they do not modify the protein sequences. However, relatively little research has specifically delineated the functionality of synonymous mutations in cancer. RESULTS: We investigated the nu...

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Detalles Bibliográficos
Autores principales: Bin, Yannan, Wang, Xiaojuan, Zhao, Le, Wen, Pengbo, Xia, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900878/
https://www.ncbi.nlm.nih.gov/pubmed/31815613
http://dx.doi.org/10.1186/s12881-019-0926-4