Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model

In glaucoma, studies revealed an involvement of the complement system. In an experimental autoimmune glaucoma model, immunization with an optic nerve homogenate antigen (ONA) led to retinal ganglion cell (RGC) loss, while intraocular pressure (IOP) remained unchanged. Here, we investigated the thera...

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Detalles Bibliográficos
Autores principales: Reinehr, Sabrina, Gomes, Sara C., Gassel, Caroline J., Asaad, M. Ali, Stute, Gesa, Schargus, Marc, Dick, H. Burkhard, Joachim, Stephanie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901014/
https://www.ncbi.nlm.nih.gov/pubmed/31849650
http://dx.doi.org/10.3389/fphar.2019.01381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901014/
https://www.ncbi.nlm.nih.gov/pubmed/31849650
http://dx.doi.org/10.3389/fphar.2019.01381

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