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Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model
In glaucoma, studies revealed an involvement of the complement system. In an experimental autoimmune glaucoma model, immunization with an optic nerve homogenate antigen (ONA) led to retinal ganglion cell (RGC) loss, while intraocular pressure (IOP) remained unchanged. Here, we investigated the thera...
Autores principales: | Reinehr, Sabrina, Gomes, Sara C., Gassel, Caroline J., Asaad, M. Ali, Stute, Gesa, Schargus, Marc, Dick, H. Burkhard, Joachim, Stephanie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901014/ https://www.ncbi.nlm.nih.gov/pubmed/31849650 http://dx.doi.org/10.3389/fphar.2019.01381 |
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