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The impact of the genetic background on gene deletion phenotypes in Saccharomyces cerevisiae

Loss‐of‐function (LoF) mutations associated with disease do not manifest equally in different individuals. The impact of the genetic background on the consequences of LoF mutations remains poorly characterized. Here, we systematically assessed the changes in gene deletion phenotypes for 3,786 gene k...

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Detalles Bibliográficos
Autores principales: Galardini, Marco, Busby, Bede P, Vieitez, Cristina, Dunham, Alistair S, Typas, Athanasios, Beltrao, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901017/
https://www.ncbi.nlm.nih.gov/pubmed/31885205
http://dx.doi.org/10.15252/msb.20198831