Cobalt Chloride Induced Apoptosis by Inhibiting GPC3 Expression via the HIF-1α/c-Myc Axis in HepG2 Cells

PURPOSE: To investigate the role of glypican-3 (GPC3) in cobalt chloride (CoCl(2))-induced cell apoptosis in hepatocellular carcinoma. METHODS: HepG2 cells were treated with CoCl(2) in the absence or presence of GPC3 plasmid transfection. Cell viability and apoptosis were assessed by MTT assay and f...

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Detalles Bibliográficos
Autores principales: Tong, Yaoyao, Tong, Kun, Zhu, Qinghong, Wu, Yuqin, Yang, Yi, Zhang, Jicai, Hu, Pei, Yan, Shirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901039/
https://www.ncbi.nlm.nih.gov/pubmed/31824173
http://dx.doi.org/10.2147/OTT.S227215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901039/
https://www.ncbi.nlm.nih.gov/pubmed/31824173
http://dx.doi.org/10.2147/OTT.S227215

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