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Spray-Dried Silica Xerogel Nanoparticles as a Promising Gastroretentive Carrier System for the Management of Chemotherapy-Induced Nausea and Vomiting

PURPOSE: The current work aimed to develop spray-dried silica xerogel nanoparticles (SXNs) as a gastroretentive carrier for the dual delivery of chlorambucil (CHL) and granisetron hydrochloride (GR). As a low-density system, it was proposed to float over gastric fluids; allowing for the retention of...

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Detalles Bibliográficos
Autores principales: Ghoneim, Amira Mohsen, Tadros, Mina Ibrahim, Alaa-Eldin, Ahmed Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901059/
https://www.ncbi.nlm.nih.gov/pubmed/31824155
http://dx.doi.org/10.2147/IJN.S232841