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Exact hypothesis testing for shrinkage-based Gaussian graphical models

MOTIVATION: One of the main goals in systems biology is to learn molecular regulatory networks from quantitative profile data. In particular, Gaussian graphical models (GGMs) are widely used network models in bioinformatics where variables (e.g. transcripts, metabolites or proteins) are represented...

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Detalles Bibliográficos
Autores principales: Bernal, Victor, Bischoff, Rainer, Guryev, Victor, Grzegorczyk, Marco, Horvatovich, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901079/
https://www.ncbi.nlm.nih.gov/pubmed/31077287
http://dx.doi.org/10.1093/bioinformatics/btz357