The mosquito melanization response requires hierarchical activation of non-catalytic clip domain serine protease homologs

Serine protease cascades regulate important insect immune responses namely melanization and Toll pathway activation. An important component of these cascades are clip-domain serine protease homologs (cSPHs), which are non-catalytic, but essential for activating the enzyme prophenoloxidase (PPO) in t...

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Detalles Bibliográficos
Autores principales: El Moussawi, Layla, Nakhleh, Johnny, Kamareddine, Layla, Osta, Mike A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901238/
https://www.ncbi.nlm.nih.gov/pubmed/31765430
http://dx.doi.org/10.1371/journal.ppat.1008194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901238/
https://www.ncbi.nlm.nih.gov/pubmed/31765430
http://dx.doi.org/10.1371/journal.ppat.1008194

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