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The mosquito melanization response requires hierarchical activation of non-catalytic clip domain serine protease homologs
Serine protease cascades regulate important insect immune responses namely melanization and Toll pathway activation. An important component of these cascades are clip-domain serine protease homologs (cSPHs), which are non-catalytic, but essential for activating the enzyme prophenoloxidase (PPO) in t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901238/ https://www.ncbi.nlm.nih.gov/pubmed/31765430 http://dx.doi.org/10.1371/journal.ppat.1008194 |