GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors

G protein-coupled receptors (GPCRs) are the most widely targeted gene family for Food and Drug Administration (FDA)-approved drugs. To assess possible roles for GPCRs in cancer, we analyzed The Cancer Genome Atlas (TCGA) data for mRNA expression, mutations, and copy number variation (CNV) in 20 cate...

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Detalles Bibliográficos
Autores principales: Sriram, Krishna, Moyung, Kevin, Corriden, Ross, Carter, Hannah, Insel, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901242/
https://www.ncbi.nlm.nih.gov/pubmed/31765370
http://dx.doi.org/10.1371/journal.pbio.3000434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901242/
https://www.ncbi.nlm.nih.gov/pubmed/31765370
http://dx.doi.org/10.1371/journal.pbio.3000434

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