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Availability of splicing factors in the nucleoplasm can regulate the release of mRNA from the gene after transcription

Gene expression dynamics can be measured in single living cells. Using a detectable transcriptionally active gene in living cells, we previously found that an mRNA undergoing several splicing events was retained at this gene after transcription until completion of mRNA processing. To determine the r...

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Detalles Bibliográficos
Autores principales: Hochberg-Laufer, Hodaya, Neufeld, Noa, Brody, Yehuda, Nadav-Eliyahu, Shani, Ben-Yishay, Rakefet, Shav-Tal, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901260/
https://www.ncbi.nlm.nih.gov/pubmed/31765392
http://dx.doi.org/10.1371/journal.pgen.1008459