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A Gene–Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis

The influence and effect of cigarette smoking in sarcoidosis is unclear. Here, we evaluated gene-environment interaction between multiple genetic variants including HLA genes and smoking in sarcoidosis defined by two clinical phenotypes, Löfgren’s syndrome (LS) and patients without Löfgren’s syndrom...

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Detalles Bibliográficos
Autores principales: Rivera, Natalia V., Patasova, Karina, Kullberg, Susanna, Diaz-Gallo, Lina Marcela, Iseda, Tomoko, Bengtsson, Camilla, Alfredsson, Lars, Eklund, Anders, Kockum, Ingrid, Grunewald, Johan, Padyukov, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901455/
https://www.ncbi.nlm.nih.gov/pubmed/31819081
http://dx.doi.org/10.1038/s41598-019-54612-1