Cargando…

A Gene–Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis

The influence and effect of cigarette smoking in sarcoidosis is unclear. Here, we evaluated gene-environment interaction between multiple genetic variants including HLA genes and smoking in sarcoidosis defined by two clinical phenotypes, Löfgren’s syndrome (LS) and patients without Löfgren’s syndrom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rivera, Natalia V., Patasova, Karina, Kullberg, Susanna, Diaz-Gallo, Lina Marcela, Iseda, Tomoko, Bengtsson, Camilla, Alfredsson, Lars, Eklund, Anders, Kockum, Ingrid, Grunewald, Johan, Padyukov, Leonid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901455/ https://www.ncbi.nlm.nih.gov/pubmed/31819081 http://dx.doi.org/10.1038/s41598-019-54612-1

Ejemplares similares

Functional link between sarcoidosis-associated gene variants and quantitative levels of bronchoalveolar lavage fluid cell types
por: Abo Al Hayja, Muntasir, et al.
Publicado: (2023)

Common variants of T-cells contribute differently to phenotypic variation in sarcoidosis
por: Rivera, Natalia V., et al.
Publicado: (2017)

Effects of infliximab on lung and circulating natural killer cells, CD56+ T cells and B cells in sarcoidosis
por: Kullberg, Susanna, et al.
Publicado: (2021)

Subpopulations of cells from bronchoalveolar lavage can predict prognosis in sarcoidosis
por: Darlington, Pernilla, et al.
Publicado: (2020)

Sex differences in the genetics of sarcoidosis across European and African ancestry populations
por: Xiong, Ying, et al.
Publicado: (2023)

Peripheral blood lymphopenia in sarcoidosis associates with HLA-DRB1 alleles but not with lung immune cells and organ involvement
por: Darlington, Pernilla, et al.
Publicado: (2023)

Lung CD4+ Vα2.3+ T-cells in sarcoidosis cohorts with Löfgren’s syndrome
por: Darlington, Pernilla, et al.
Publicado: (2020)

Sarcoidosis mortality in Sweden: a population-based cohort study
por: Rossides, Marios, et al.
Publicado: (2018)

High-intensity resistance training in newly diagnosed sarcoidosis- an exploratory study of effects on lung function, muscle strength, fatigue, dyspnea, health-related quality of life and lung immune cells
por: Kullberg, Susanna, et al.
Publicado: (2020)

Changes in lung immune cells related to clinical outcome during treatment with infliximab for sarcoidosis
por: Kullberg, S., et al.
Publicado: (2020)

GEIRA: gene-environment and gene–gene interaction research application
por: Ding, Bo, et al.
Publicado: (2011)

Maternal and infant outcomes in sarcoidosis pregnancy: a Swedish population-based cohort study of first births
por: Köcher, Laura, et al.
Publicado: (2020)

Risk of first and recurrent serious infection in sarcoidosis: a Swedish register-based cohort study
por: Rossides, Marios, et al.
Publicado: (2020)

Risk and predictors of heart failure in sarcoidosis in a population-based cohort study from Sweden
por: Rossides, Marios, et al.
Publicado: (2022)

Genes and environment in arthritis: can RA be prevented?
por: Klareskog, Lars, et al.
Publicado: (2002)

Different HLA-DRB1 allele distributions in distinct clinical subgroups of sarcoidosis patients
por: Grunewald, Johan, et al.
Publicado: (2010)

Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case–control study
por: Sverdrup, Berit, et al.
Publicado: (2005)

Infection risk in sarcoidosis patients treated with methotrexate compared to azathioprine: A retrospective ‘target trial’ emulated with Swedish real‐world data
por: Rossides, Marios, et al.
Publicado: (2021)

Are infectious diseases risk factors for sarcoidosis or a result of reverse causation? Findings from a population-based nested case–control study
por: Rossides, Marios, et al.
Publicado: (2020)

Expression Profile of Six RNA-Binding Proteins in Pulmonary Sarcoidosis
por: Navratilova, Zdenka, et al.
Publicado: (2016)

Reproductive and hormonal risk factors for sarcoidosis: a nested case–control study
por: Dehara, Marina, et al.
Publicado: (2022)

Genetic Association with ERAP1 in Psoriasis Is Confined to Disease Onset after Puberty and Not Dependent on HLA-C*06
por: Lysell, Josefin, et al.
Publicado: (2013)

Sarcoidosis exosomes stimulate monocytes to produce pro-inflammatory cytokines and CCL2
por: Wahlund, Casper J. E., et al.
Publicado: (2020)

Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA‐DRB1 Genotype Associations and Immunological and Clinical Manifestations
por: Diaz‐Gallo, Lina‐Marcela, et al.
Publicado: (2021)

Occupational exposure to textile dust increases the risk of rheumatoid arthritis: results from a Malaysian population-based case–control study
por: Too, Chun Lai, et al.
Publicado: (2016)

Monocytes in sarcoidosis are potent tumour necrosis factor producers and predict disease outcome
por: Lepzien, Rico, et al.
Publicado: (2021)

Effects of GSTM1 in Rheumatoid Arthritis; Results from the Swedish EIRA study
por: Lundström, Emeli, et al.
Publicado: (2011)

Organic solvents and MS susceptibility: Interaction with MS risk HLA genes
por: Hedström, Anna Karin, et al.
Publicado: (2018)

A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity
por: Olsson, Lina M, et al.
Publicado: (2007)

Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis
por: Diaz-Gallo, Lina-Marcela, et al.
Publicado: (2018)

Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis
por: Snir, Omri, et al.
Publicado: (2014)

Analysis of Neuropeptide S Receptor Gene (NPSR1) Polymorphism in Rheumatoid Arthritis
por: D'Amato, Mauro, et al.
Publicado: (2010)

Cardiac involvement in Caucasian patients with pulmonary sarcoidosis
por: Darlington, Pernilla, et al.
Publicado: (2014)

Interaction between adolescent obesity and HLA risk genes in the etiology of multiple sclerosis
por: Hedström, Anna Karin, et al.
Publicado: (2014)

SNP Variants in Major Histocompatibility Complex Are Associated with Sarcoidosis Susceptibility—A Joint Analysis in Four European Populations
por: Wolin, Annika, et al.
Publicado: (2017)

Genetic Influences in Cancer‐Associated Myositis
por: Patasova, Karina, et al.
Publicado: (2022)

Interaction between passive smoking and two HLA genes with regard to multiple sclerosis risk
por: Hedström, Anna Karin, et al.
Publicado: (2014)

Distinct HLA associations with autoantibody-defined subgroups in idiopathic inflammatory myopathies
por: Leclair, Valérie, et al.
Publicado: (2023)

Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis
por: Shchetynsky, Klementy, et al.
Publicado: (2017)

Cigarette smoking patterns preceding primary Sjögren’s syndrome
por: Mofors, Johannes, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7hk6e175p9gqafs0qn0f3iqsmi