Cargando…
lncRNA-ZFAS1 induces mitochondria-mediated apoptosis by causing cytosolic Ca(2+) overload in myocardial infarction mice model
Previously, we have identified ZFAS1 as a potential new long non-coding RNA (lncRNA) biomarker of acute myocardial infarction (MI) and as a sarcoplasmic reticulum Ca(2+)-ATPase 2a (SERCA2a) inhibitor, causing intracellular Ca(2+) overload and contractile dysfunction in a mouse model of MI. In the cu...
Autores principales: | , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901475/ https://www.ncbi.nlm.nih.gov/pubmed/31819041 http://dx.doi.org/10.1038/s41419-019-2136-6 |