lncRNA-ZFAS1 induces mitochondria-mediated apoptosis by causing cytosolic Ca(2+) overload in myocardial infarction mice model

Previously, we have identified ZFAS1 as a potential new long non-coding RNA (lncRNA) biomarker of acute myocardial infarction (MI) and as a sarcoplasmic reticulum Ca(2+)-ATPase 2a (SERCA2a) inhibitor, causing intracellular Ca(2+) overload and contractile dysfunction in a mouse model of MI. In the cu...

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Detalles Bibliográficos
Autores principales: Jiao, Lei, Li, Mengmeng, Shao, Yingchun, Zhang, Yuanyuan, Gong, Manyu, Yang, Xuewen, Wang, Yanying, Tan, Zhongyue, Sun, Lihua, Xuan, Lina, Yu, Qi, Li, Yanru, Gao, Yuqiu, Liu, Heng, Xu, Honglin, Li, Xiaohan, Zhang, Yong, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901475/
https://www.ncbi.nlm.nih.gov/pubmed/31819041
http://dx.doi.org/10.1038/s41419-019-2136-6

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