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Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum

Human myeloid-derived growth factor (hMYDGF) is a 142-residue protein with a C-terminal endoplasmic reticulum (ER) retention sequence (ERS). Extracellular MYDGF mediates cardiac repair in mice after anoxic injury. Although homologs of hMYDGF are found in eukaryotes as distant as protozoans, its stru...

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Detalles Bibliográficos
Autores principales: Bortnov, Valeriu, Tonelli, Marco, Lee, Woonghee, Lin, Ziqing, Annis, Douglas S., Demerdash, Omar N., Bateman, Alex, Mitchell, Julie C., Ge, Ying, Markley, John L., Mosher, Deane F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901522/
https://www.ncbi.nlm.nih.gov/pubmed/31819058
http://dx.doi.org/10.1038/s41467-019-13577-5