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Neonatal obstructive nephropathy induces necroptosis and necroinflammation

Urinary tract obstruction during kidney development causes tubular apoptosis, tubular necrosis, and interstitial inflammation. Necroptosis is a subtype of programmed necrosis mediated by the receptor-interacting serine/threonine-protein kinase-3 (RIPK3) and the pseudokinase mixed lineage kinase doma...

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Detalles Bibliográficos
Autores principales: Popper, Bastian, Rammer, Marian Theodor, Gasparitsch, Mojca, Singer, Teresa, Keller, Ursula, Döring, Yvonne, Lange-Sperandio, Bärbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901532/
https://www.ncbi.nlm.nih.gov/pubmed/31819111
http://dx.doi.org/10.1038/s41598-019-55079-w