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Bone secreted factors induce cellular quiescence in prostate cancer cells

Disseminated tumor cells (DTCs) undergo a dormant state in the distant metastatic site(s) before becoming overt metastatic diseases. In prostate cancer (PCa), bone metastasis can occur years after prostatectomy, suggesting that bone may provide dormancy-inducing factors. To search for these factors,...

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Detalles Bibliográficos
Autores principales: Yu-Lee, Li-Yuan, Lee, Yu-Chen, Pan, Jing, Lin, Song-Chang, Pan, Tianhong, Yu, Guoyu, Hawke, David H., Pan, Bih-Fang, Lin, Sue-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901558/
https://www.ncbi.nlm.nih.gov/pubmed/31819067
http://dx.doi.org/10.1038/s41598-019-54566-4