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BRD4 promotes tumor progression and NF-κB/CCL2-dependent tumor-associated macrophage recruitment in GIST

The most commonly occurring sarcoma of the soft tissue is gastrointestinal stromal tumor (GIST). Treatment and prevention of the disease necessitate an understanding of the molecular mechanisms involved. However, the role of BRD4 in the progression of GIST is still unclear. While it is known there a...

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Detalles Bibliográficos
Autores principales: Mu, Jianfeng, Sun, Pengfei, Ma, Zhiming, Sun, Pengda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901583/
https://www.ncbi.nlm.nih.gov/pubmed/31819043
http://dx.doi.org/10.1038/s41419-019-2170-4